Publications

2022

Asensi-Cantó A, López-Abellán MD, Castillo-Guardiola V, Hurtado AM, Martínez-Penella M, Luengo-Gil G, Conesa-Zamora P. Antitumoral Effects of Tricyclic Antidepressants: Beyond Neuropathic Pain Treatment. Cancers (Basel). 2022 Jul 1;14(13):3248. doi: 10.3390/cancers14133248. PMID: 35805019; PMCID: PMC9265090.

Navarro-Manzano E, Luengo-Gil G, González-Conejero R, García-Garre E, García-Martínez E, García-Torralba E, Chaves-Benito A, Vicente V, Ayala de la Peña F. Prognostic and Predictive Effects of Tumor and Plasma miR-200c-3p in Locally Advanced and Metastatic Breast Cancer. Cancers (Basel). 2022 May 12;14(10):2390. doi: 10.3390/cancers14102390. PMID: 35625994; PMCID: PMC9139340.

de Alarcón R, Alburquerque-González B, Fernández-Valera Á, Molina-Nuñez M, Álvarez Fernandez G, Consuegra-Sánchez L, Luengo-Gil G, Conesa-Zamora P. Pharmacogenetic role of vitamin D-binding protein and vitamin D receptor polymorphisms in the treatment response of dialysis patients with secondary hyperparathyroidism. Nephrol Dial Transplant. 2022 Mar 25;37(4):792-795. doi: 10.1093/ndt/gfab353. PMID: 34888693.

Zaragoza-Huesca D, Garrido-Rodríguez P, Jiménez-Fonseca P, Martínez de Castro E, Sánchez-Cánovas M, Visa L, Custodio A, Fernández-Montes A, Peñas-Martínez J, Morales Del Burgo P, Gallego J, Luengo-Gil G, Vicente V, Martínez-Martínez I, Carmona-Bayonas A. Identification of Thrombosis-Related Genes in Patients with Advanced Gastric Cancer: Data from AGAMENON-SEOM Registry. Biomedicines. 2022 Jan 11;10(1):148. doi: 10.3390/biomedicines10010148. PMID: 35052827; PMCID: PMC8773420.

2021

Luengo-Gil G, Conesa-Zamora P. Potential Utility of Induced Translocation of Engineered Bacteria as a Therapeutic Agent for Mounting a Personalized Neoantigen-Based Tumor Immune Response. Glob Chall. 2021 Dec 16;6(3):2100051. doi: 10.1002/gch2.202100051. PMID: 35284089; PMCID: PMC8902290.

Sánchez-Maldonado JM, Cáliz R, López-Nevot MÁ, Cabrera-Serrano AJ, Moñiz-Díez A, Canhão H, Ter Horst R, Quartuccio L, Sorensen SB, Glintborg B, Hetland ML, Filipescu I, Pérez-Pampin E, Conesa-Zamora P, Swierkot J, den Broeder AA, De Vita S, Petersen ERB, Li Y, Ferrer MA, Escudero A, Netea MG, Coenen MJH, Andersen V, Fonseca JE, Jurado M, Bogunia-Kubik K, Collantes E, Sainz J. Validation of GWAS-Identified Variants for Anti-TNF Drug Response in Rheumatoid Arthritis: A Meta-Analysis of Two Large Cohorts. Front Immunol. 2021 Oct 27;12:672255. doi: 10.3389/fimmu.2021.672255. PMID: 34777329; PMCID: PMC8579100.

Turpín-Sevilla MDC, Pérez-Sanz F, García-Solano J, Sebastián-León P, Trujillo-Santos J, Carbonell P, Estrada E, Tuomisto A, Herruzo I, Fennell LJ, Mäkinen MJ, Rodríguez-Braun E, Whitehall VLJ, Conesa A, Conesa-Zamora P. Global Methylome Scores Correlate with Histological Subtypes of Colorectal Carcinoma and Show Different Associations with Common Clinical and Molecular Features. Cancers (Basel). 2021 Oct 14;13(20):5165. doi: 10.3390/cancers13205165. PMID: 34680315; PMCID: PMC8533997.

Guirao-Abad JP, Weichert M, Luengo-Gil G, Sze Wah Wong S, Aimanianda V, Grisham C, Malev N, Reddy S, Woollett L, Askew DS. Pleiotropic Effects of the P5-Type ATPase SpfA on Stress Response Networks Contribute to Virulence in the Pathogenic Mold Aspergillus fumigatus. mBio. 2021 Oct 26;12(5):e0273521. doi: 10.1128/mBio.02735-21. Epub 2021 Oct 19. PMID: 34663092; PMCID: PMC8524344.

Santaclara V, Torres-Moreno D, Bernal-Mañas CM, Isaac MA, Ortiz-Reina S, Conesa-Zamora P. Relationship between polymorphisms in the FAS/FASL death receptor system and progression of low-grade precursor lesions infected with high-risk human papilloma virus. Hum Immunol. 2021 Sep;82(9):621-624. doi: 10.1016/j.humimm.2021.06.002. Epub 2021 Jun 12. PMID: 34127318.

Wahab A, Hyytiäinen A, Wahbi W, Tuomainen K, Tervo S, Conesa-Zamora P, Jauhiainen L, Mäkinen LK, Paavonen T, Toppila-Salmi S, Salem A, Almangush A, Salo T, Al-Samadi A. The effect of fascin 1 inhibition on head and neck squamous cell carcinoma cells. Eur J Oral Sci. 2021 Dec;129(6):e12819. doi: 10.1111/eos.12819. Epub 2021 Aug 4. PMID: 34346523.

Peñas-Martínez J, Luengo-Gil G, Espín S, Bohdan N, Ortega-Sabater C, Ródenas MC, Zaragoza-Huesca D, López-Andreo MJ, Plasencia C, Vicente V, Carmona-Bayonas A, Martínez-Martínez I. Anti-Tumor Functions of Prelatent Antithrombin on Glioblastoma Multiforme Cells. Biomedicines. 2021 May 7;9(5):523. doi: 10.3390/biomedicines9050523. PMID: 34067120; PMCID: PMC8151964.

Alburquerque-González B, Bernabé-García Á, Bernabé-García M, Ruiz-Sanz J, López-Calderón FF, Gonnelli L, Banci L, Peña-García J, Luque I, Nicolás FJ, Cayuela-Fuentes ML, Luchinat E, Pérez-Sánchez H, Montoro-García S, Conesa-Zamora P. The FDA-Approved Antiviral Raltegravir Inhibits Fascin1-Dependent Invasion of Colorectal Tumor Cells In Vitro and In Vivo. Cancers (Basel). 2021 Feb 18;13(4):861. doi: 10.3390/cancers13040861. PMID: 33670655; PMCID: PMC7921938.

García de Guadiana-Romualdo L, Calvo Nieves MD, Rodríguez Mulero MD, Calcerrada Alises I, Hernández Olivo M, Trapiello Fernández W, González Morales M, Bolado Jiménez C, Albaladejo-Otón MD, Fernández Ovalle H, Conesa Hernández A, Azpeleta Manrique E, Consuegra-Sánchez L, Nogales Martín L, Conesa Zamora P, Andaluz-Ojeda D. MR-proADM as marker of endotheliitis predicts COVID-19 severity. Eur J Clin Invest. 2021 May;51(5):e13511. doi: 10.1111/eci.13511. Epub 2021 Feb 20. PMID: 33569769; PMCID: PMC7995076.

Luis García de Guadiana Romualdo, Mulero MDR, Olivo MH, Rojas CR, Arenas VR, Morales MG, Abellán AB, Conesa-Zamora P, García-García J, Hernández AC, Morell-García D, Dolores Albaladejo-Otón M, Consuegra-Sánchez L. Circulating levels of GDF-15 and calprotectin for prediction of in-hospital mortality in COVID-19 patients: A case series. J Infect. 2021 Feb;82(2):e40-e42. doi: 10.1016/j.jinf.2020.08.010. Epub 2020 Aug 12. PMID: 32795482; PMCID: PMC7419246.

Águila S, Noto R, Luengo-Gil G, Espín S, Bohdan N, de la Morena-Barrio ME, Peñas J, Rodenas MC, Vicente V, Corral J, Manno M, Martínez-Martínez I. N-Glycosylation as a Tool to Study Antithrombin Secretion, Conformation, and Function. Int J Mol Sci. 2021 Jan 6;22(2):516. doi: 10.3390/ijms22020516. PMID: 33419227; PMCID: PMC7825591.

2020

Hurtado López AM, Chen-Liang TH, Zurdo M, Carrillo-Tornel S, Panadero J, Salido EJ, Beltrán V, Muiña B, Amigo M, Navarro-Villamor N, Cifuentes R, Calabria I, Antón AI, Teruel R, Muro M, Vicente V, Jerez A. Cancer testis antigens in myelodysplastic syndromes revisited: a targeted RNA-seq approach. Oncoimmunology. 2020 Oct 1;9(1):1824642. doi: 10.1080/2162402X.2020.1824642. PMID: 33101773; PMCID: PMC7553508.

Galan-Ros J, Ramos-Arenas V, Conesa-Zamora P. Predictive values of colon microbiota in the treatment response to colorectal cancer. Pharmacogenomics. 2020 Sep;21(14):1045-1059. doi: 10.2217/pgs-2020-0044. Epub 2020 Sep 8. PMID: 32896201.

Kondelova A, Alburquerque-González B, Vychytilova-Faltejskova P, García-Solano J, Prochazka V, Kala Z, Pérez F, Slaby O, Conesa-Zamora P. miR-181a-2* expression is different amongst carcinomas from the colorectal serrated route. Mutagenesis. 2020 Jul 11;35(3):233-241. doi: 10.1093/mutage/gez039. PMID: 31784758.

Alburquerque-González B, López-Calderón FF, López-Abellán MD, Esteban-Gil Á, García-Solano J, Conesa-Zamora P. Biology and Therapeutic Targets of Colorectal Serrated Adenocarcinoma; Clues for a Histologically Based Treatment against an Aggressive Tumor. Int J Mol Sci. 2020 Mar 14;21(6):1991. doi: 10.3390/ijms21061991. PMID: 32183342; PMCID: PMC7139914.

Manuel Sánchez-Maldonado J, Martínez-Bueno M, Canhão H, Ter Horst R, Muñoz-Peña S, Moñiz-Díez A, Rodríguez-Ramos A, Escudero A, Sorensen SB, Hetland ML, Ferrer MA, Glintborg B, Filipescu I, Pérez-Pampin E, Conesa-Zamora P, García A, den Broeder A, De Vita S, Hove Jacobsen SE, Collantes E, Quartuccio L, Netea MG, Li Y, Fonseca JE, Jurado M, López-Nevot MÁ, Coenen MJH, Andersen V, Cáliz R, Sainz J. NFKB2 polymorphisms associate with the risk of developing rheumatoid arthritis and response to TNF inhibitors: Results from the REPAIR consortium. Sci Rep. 2020 Mar 9;10(1):4316. doi: 10.1038/s41598-020-61331-5. PMID: 32152480; PMCID: PMC7062729.

Luis García de Guadiana Romualdo, Mulero MDR, Olivo MH, Rojas CR, Arenas VR, Morales MG, Abellán AB, Conesa-Zamora P, García-García J, Hernández AC, Morell-García D, Dolores Albaladejo-Otón M, Consuegra-Sánchez L. Circulating levels of GDF-15 and calprotectin for prediction of in-hospital mortality in COVID-19 patients: A case series. J Infect. 2021 Feb;82(2):e40-e42. doi: 10.1016/j.jinf.2020.08.010. Epub 2020 Aug 12. PMID: 32795482; PMCID: PMC7419246.

Alburquerque-González B, Bernabé-García M, Montoro-García S, Bernabé-García Á, Rodrigues PC, Ruiz Sanz J, López-Calderón FF, Luque I, Nicolas FJ, Cayuela ML, Salo T, Pérez-Sánchez H, Conesa-Zamora P. New role of the antidepressant imipramine as a Fascin1 inhibitor in colorectal cancer cells. Exp Mol Med. 2020 Feb;52(2):281-292. doi: 10.1038/s12276-020-0389-x. Epub 2020 Feb 20. PMID: 32080340; PMCID: PMC7062870.

Montoro-García S, Alburquerque-González B, Bernabé-García Á, Bernabé-García M, Rodrigues PC, den-Haan H, Luque I, Nicolás FJ, Pérez-Sánchez H, Cayuela ML, Salo T, Conesa-Zamora P. Novel anti-invasive properties of a Fascin1 inhibitor on colorectal cancer cells. J Mol Med (Berl). 2020 Mar;98(3):383-394. doi: 10.1007/s00109-020-01877-z. Epub 2020 Jan 29. PMID: 31996952.

2019

Vallejo F, Yuste JE, Teruel-Montoya R, Luengo-Gil G, Bohdan N, Espín S, García-Barberá N, Martínez C, Vicente V, Espín JC, Martínez-Martínez I. First exploratory study on the metabolome from plasma exosomes in patients with paroxysmal nocturnal hemoglobinuria. Thromb Res. 2019 Nov;183:80-85. doi: 10.1016/j.thromres.2019.10.001. Epub 2019 Oct 28. PMID: 31671376.

Esteban-Gil A, Pérez-Sanz F, García-Solano J, Alburquerque-González B, Parreño-González MA, Legaz-García MDC, Fernández-Breis JT, Rodriguez-Braun E, Pimentel P, Tuomisto A, Mäkinen M, Slaby O, Conesa-Zamora P. ColPortal, an integrative multiomic platform for analysing epigenetic interactions in colorectal cancer. Sci Data. 2019 Oct 31;6(1):255. doi: 10.1038/s41597-019-0198-z. PMID: 31672979; PMCID: PMC6823353.

Iniesta P, Revilla N, Chen-Liang TH, Hurtado AM, Vicente V, Heras I, Jerez A, Lozano ML. An early increase of CD56bright natural killer subset as dominant effect and predictor of response to extracorporeal photopheresis for graft-versus-host disease. Transfusion. 2018 Dec;58(12):2924-2932. doi: 10.1111/trf.14964. Epub 2018 Sep 27. PMID: 30260547.

Sastre Lozano VM, Morán Sánchez S, García Solano J, Conesa Zamora P, Ruiz Merino G. Relationship between the polyp detection rate and the post-colonoscopy colorectal cancer rate. Rev Esp Enferm Dig. 2019 Aug;111(8):598-602. doi: 10.17235/reed.2019.5889/2018. PMID: 31190550.

Luengo-Gil G, García-Andreo AB, Ortega-Sabater C, Bohdan N, Espín S, Peñas-Martínez J, Martínez-Planes E, García-Hernández Á, Vicente V, Quintanilla M, Martínez-Martínez I. Antithrombin is incorporated into exosomes produced by antithrombin non-expressing cells. Biochimie. 2019 Oct;165:245-249. doi: 10.1016/j.biochi.2019.08.010. Epub 2019 Aug 21. PMID: 31445073.

García-Solano J, Turpin-Sevilla MDC, García-García F, Carbonell-Muñoz R, Torres-Moreno D, Conesa A, Conesa-Zamora P. Differences in gene expression profiling and biomarkers between histological colorectal carcinoma subsets from the serrated pathway. Histopathology. 2019 Oct;75(4):496-507. doi: 10.1111/his.13889. Epub 2019 Aug 2. PMID: 31025430.

Caballero JC, Sánchez Barba M, Hernández Sánchez JM, Such E, Janusz K, Sanz G, Cabrero M, Chillón C, Cervera J, Hurtado AM, Jerez A, Calderón Cabrera C, Valcárcel D, Lumbreras E, Abáigar M, López Cadenas F, Hernández Rivas JM, Del Cañizo MC, Díez Campelo M. Chronic graft-versus-host disease could ameliorate the impact of adverse somatic mutations in patients with myelodysplastic syndromes and hematopoietic stem cell transplantation. Ann Hematol. 2019 Sep;98(9):2151-2162. doi: 10.1007/s00277-019-03751-6. Epub 2019 Jul 16. PMID: 31312927.

Hernández Roca M, Pérez Pallarés J, Prieto Merino D, Valdivia Salas MDM, García Solano J, Fernández Álvarez J, Lozano Vicente D, Wasniewski S, Martínez Díaz JJ, Elías Torregrosa C, Santa Cruz Siminiani A. Diagnostic Value of Elastography and Endobronchial Ultrasound in the Study of Hilar and Mediastinal Lymph Nodes. J Bronchology Interv Pulmonol. 2019 Jul;26(3):184-192. doi: 10.1097/LBR.0000000000000550. PMID: 30303859.

Hernández Roca M, Pérez Pallarés J, Valdivia Salas MDM, García Solano J, Prieto Merino D, Martínez Díaz JJ, Santa Cruz Siminiani A. Endobronchial ultrasound elastography for diagnosing mediastinal and hilar lymph nodes. Med Clin (Barc). 2020 Jan 24;154(2):45-51. English, Spanish. doi: 10.1016/j.medcli.2019.03.037. Epub 2019 Jun 25. PMID: 31253479.

Luengo-Gil G, García-Martínez E, Chaves-Benito A, Conesa-Zamora P, Navarro-Manzano E, González-Billalabeitia E, García-Garre E, Martínez-Carrasco A, Vicente V, Ayala de la Peña F. Clinical and biological impact of miR-18a expression in breast cancer after neoadjuvant chemotherapy. Cell Oncol (Dordr). 2019 Oct;42(5):627-644. doi: 10.1007/s13402-019-00450-2. Epub 2019 May 21. PMID: 31115881.

Teruel-Montoya R, Luengo-Gil G, Vallejo F, Yuste JE, Bohdan N, García-Barberá N, Espín S, Martínez C, Espín JC, Vicente V, Martínez-Martínez I. Differential miRNA expression profile and proteome in plasma exosomes from patients with paroxysmal nocturnal hemoglobinuria. Sci Rep. 2019 Mar 5;9(1):3611. doi: 10.1038/s41598-019-40453-5. PMID: 30837665; PMCID: PMC6401143.

Canet LM, Sánchez-Maldonado JM, Cáliz R, Rodríguez-Ramos A, Lupiañez CB, Canhão H, Martínez-Bueno M, Escudero A, Segura-Catena J, Sorensen SB, Hetland ML, Soto-Pino MJ, Ferrer MA, García A, Glintborg B, Filipescu I, Pérez-Pampin E, González-Utrilla A, Nevot MÁL, Conesa-Zamora P, Broeder AD, De Vita S, Jacobsen SEH, Collantes-Estevez E, Quartuccio L, Canzian F, Fonseca JE, Coenen MJH, Andersen V, Sainz J. Polymorphisms at phase I-metabolizing enzyme and hormone receptor loci influence the response to anti-TNF therapy in rheumatoid arthritis patients. Pharmacogenomics J. 2019 Feb;19(1):83-96. doi: 10.1038/s41397-018-0057-x. Epub 2018 Oct 5. Erratum in: Pharmacogenomics J. 2019 Feb 14;: PMID: 30287909.

2018

Fernández-Caballero M, Salmerón D, Dolores Chirlaque M, Chen-Liang TH, Hurtado AM, García Malo MD, Ortuño FJ, Roldán V, Vicente V, Jerez A, De Arriba F. Increasing therapy-related myeloid neoplasms in multiple myeloma. Eur J Clin Invest. 2019 Feb;49(2):e13050. doi: 10.1111/eci.13050. Epub 2018 Dec 7. PMID: 30422316.

García-Solano J, Turpin MC, Torres-Moreno D, Huertas-López F, Tuomisto A, Mäkinen MJ, Conesa A, Conesa-Zamora P. Two histologically colorectal carcinomas subsets from the serrated pathway show different methylome signatures and diagnostic biomarkers. Clin Epigenetics. 2018 Nov 9;10(1):141. doi: 10.1186/s13148-018-0571-3. PMID: 30413173; PMCID: PMC6230233..

Wasniewski S, Consuegra-Sánchez L, Conesa-Zamora P, García de Guadiana-Romualdo L, Ramos-Ruiz P, Merelo-Nicolás M, Clavel-Ruipérez FG, Alburquerque-González B, Soria-Arcos F, Castillo-Moreno JA. Low Performance of a Clinical-Genetic Model in the Estimation of Time in Therapeutic Range in Acenocoumarol-Adherent Patients with Nonvalvular Atrial Fibrillation: The Quality of Anticoagulation Challenge. Biomed Res Int. 2018 Oct 17;2018:8012747. doi: 10.1155/2018/8012747. PMID: 30417015; PMCID: PMC6207892.

Hurtado AM, Luengo-Gil G, Chen-Liang TH, Amaral F, Batta K, Palomo L, Lumbreras E, Przychodzen B, Caparros E, Amigo ML, Dıez-Campelo M, Zamora L, Salido Fierrez EJ, Maciejewski JP, Ortuño FJ, Vicente V, Del Canizo M, Sole F, Ferrer-Marin F, Wiseman DH, Jerez A. Transcriptomic rationale for synthetic lethality-targeting ERCC1 and CDKN1A in chronic myelomonocytic leukaemia. Br J Haematol. 2018 Aug;182(3):373-383. doi: 10.1111/bjh.15408. Epub 2018 May 24. PMID: 29797327; PMCID: PMC8404555.

Chen-Liang TH, Casado-Prieto AM, Campos-Rodríguez V, Hurtado AM, Amigo ML, García-Malo MD, Vicente V, Ortuño FJ, Jerez A. An increased percentage of myeloid CD34+ bone marrow cells stratifies intermediate IPSS-R myelodysplastic syndrome patients into prognostically significant groups. Int J Lab Hematol. 2018 Oct;40(5):549-555. doi: 10.1111/ijlh.12860. Epub 2018 May 18. PMID: 29774987.

Luengo-Gil G, Gonzalez-Billalabeitia E, Perez-Henarejos SA, Navarro Manzano E, Chaves-Benito A, Garcia-Martinez E, Garcia-Garre E, Vicente V, Ayala de la Peña F. Angiogenic role of miR-20a in breast cancer. PLoS One. 2018 Apr 4;13(4):e0194638. doi: 10.1371/journal.pone.0194638. PMID: 29617404; PMCID: PMC5884522.

Martínez-Losada C, Serrano-López J, Serrano-López J, Noguera NI, Garza E, Piredda L, Lavorgna S, Consalvo MAI, Ottone T, Alfonso V, Peinado JR, Garcia-Ortiz MV, Morales-Ruiz T, Jérez A, Hurtado AM, Montesinos P, Cervera J, Such E, Ibañez M, Sempere A, Sanz MÁ, Lo-Coco F, Sánchez-García J. Clonal genetic evolution at relapse of favorable-risk acute myeloid leukemia with NPM1 mutation is associated with phenotypic changes and worse outcomes. Haematologica. 2018 Sep;103(9):e400-e403. doi: 10.3324/haematol.2018.188433. Epub 2018 Apr 5. PMID: 29622659; PMCID: PMC6119134.

García Garre E, Luengo Gil G, Montoro García S, Gonzalez Billalabeitia E, Zafra Poves M, García Martinez E, Roldán Schilling V, Navarro Manzano E, Ivars Rubio A, Lip GYH, Ayala de la Peña F. Circulating small-sized endothelial microparticles as predictors of clinical outcome after chemotherapy for breast cancer: an exploratory analysis. Breast Cancer Res Treat. 2018 May;169(1):83-92. doi: 10.1007/s10549-017-4656-z. Epub 2018 Jan 16. PMID: 29340882.

Romero-Cara P, Torres-Moreno D, Pedregosa J, Vílchez JA, García-Simón MS, Ruiz-Merino G, Morán-Sanchez S, Conesa-Zamora P. A FCGR3A Polymorphism Predicts Anti-drug Antibodies in Chronic Inflammatory Bowel Disease Patients Treated With Anti-TNF. Int J Med Sci. 2018 Jan 1;15(1):10-15. doi: 10.7150/ijms.22812. PMID: 29333082; PMCID: PMC5765734.

2017

Vychytilova-Faltejskova P, Merhautova J, Machackova T, Gutierrez-Garcia I, Garcia-Solano J, Radova L, Brchnelova D, Slaba K, Svoboda M, Halamkova J, Demlova R, Kiss I, Vyzula R, Conesa-Zamora P, Slaby O. MiR-215-5p is a tumor suppressor in colorectal cancer targeting EGFR ligand epiregulin and its transcriptional inducer HOXB9. Oncogenesis. 2017 Dec 4;6(11):399. doi: 10.1038/s41389-017-0006-6. PMID: 29199273; PMCID: PMC5868056.

Barh D, García-Solano ME, Tiwari S, Bhattacharya A, Jain N, Torres-Moreno D, Ferri B, Silva A, Azevedo V, Ghosh P, Blum K, Conesa-Zamora P, Perry G. BARHL1 Is Downregulated in Alzheimer’s Disease and May Regulate Cognitive Functions through ESR1 and Multiple Pathways. Genes (Basel). 2017 Sep 28;8(10):245. doi: 10.3390/genes8100245. PMID: 28956815; PMCID: PMC5664095.

B Arroyo A, Salloum-Asfar S, Pérez-Sánchez C, Teruel-Montoya R, Navarro S, García-Barberá N, Luengo-Gil G, Roldán V, Hansen JB, López-Pedrera C, Vicente V, González-Conejero R, Martínez C. Regulation of TFPIα expression by miR-27a/b-3p in human endothelial cells under normal conditions and in response to androgens. Sci Rep. 2017 Feb 27;7:43500. doi: 10.1038/srep43500. PMID: 28240250; PMCID: PMC5327489.

García-Lagunar MH, Consuegra-Sánchez L, Conesa-Zamora P, Ruiz-Cosano J, Soria-Arcos F, García de Guadiana L, Vivar PC, Castillo-Moreno JA, Melgarejo-Moreno A. Genotyping of six clopidogrel-metabolizing enzyme polymorphisms has a minor role in the assessment of platelet reactivity in patients with acute coronary syndrome. Anatol J Cardiol. 2017 Apr;17(4):303-312. doi: 10.14744/AnatolJCardiol.2016.7390. Epub 2017 Feb 1. PMID: 28179614; PMCID: PMC5469111.

Gutiérrez-Cívicos R, Hurtado AM, Torres-Moreno D, Sanchez-Blanco JJ, Español I, Consuegra-Sánchez L, Perez-Ceballos E, Gutiérrez-Meca MD, Jerez A, Conesa-Zamora P. Rituximab response in follicular lymphoma is associated with the rs20575 polymorphism in TRAILR1 extrinsic apoptosis trigger. Pharmacogenet Genomics. 2017 Feb;27(2):70-77. doi: 10.1097/FPC.0000000000000262. PMID: 27977511.

Bullich G, Vargas I, Trujillano D, Mendizábal S, Piñero-Fernández JA, Fraga G, García-Solano J, Ballarín J, Estivill X, Torra R, Ars E. Contribution of the TTC21B gene to glomerular and cystic kidney diseases. Nephrol Dial Transplant. 2017 Jan 1;32(1):151-156. doi: 10.1093/ndt/gfv453. PMID: 26940125.

2016

García-Lagunar MH, Gutiérrez-Cívicos MR, García-Simón MS, Conesa-Zamora P, Jimenez-Santos E, Cano-Vivar P, García-Márquez A, Muñoz-García I, Viney AC. Reasons for Discontinuation and Adverse Effects of TNFα Inhibitors in a Cohort of Patients With Rheumatoid Arthritis and Ankylosing Spondylitis. Ann Pharmacother. 2017 May;51(5):388-393. doi: 10.1177/1060028016682330. Epub 2016 Dec 5. PMID: 27920336.

Tuomisto A, García-Solano J, Sirniö P, Väyrynen J, Pérez-Guillermo M, Mäkinen MJ, Conesa-Zamora P. HIF-1α expression and high microvessel density are characteristic features in serrated colorectal cancer. Virchows Arch. 2016 Oct;469(4):395-404. doi: 10.1007/s00428-016-1988-8. Epub 2016 Jul 15. PMID: 27421843.

Dominguez-Rodriguez A, Abreu-Gonzalez P, Consuegra-Sanchez L, Avanzas P, Sanchez-Grande A, Conesa-Zamora P. Thrombus Aspirated from Patients with ST-Elevation Myocardial Infarction: Association between 3-Nitrotyrosine and Inflammatory Markers – Insights from ARTERIA Study. Int J Med Sci. 2016 Jun 18;13(7):477-82. doi: 10.7150/ijms.15463. PMID: 27429583; PMCID: PMC4946117.

Luengo-Gil G, Calvo MI, Martín-Villar E, Águila S, Bohdan N, Antón AI, Espín S, Ayala de la Peña F, Vicente V, Corral J, Quintanilla M, Martínez-Martínez I. Antithrombin controls tumor migration, invasion and angiogenesis by inhibition of enteropeptidase. Sci Rep. 2016 Jun 8;6:27544. doi: 10.1038/srep27544. PMID: 27270881; PMCID: PMC4897635.

Gutiérrez-Cívicos R, Hurtado AM, Torres-Moreno D, Sanchez-Blanco JJ, Español I, Consuegra-Sánchez L, Perez-Ceballos E, Gutiérrez-Meca MD, Jerez A, Conesa-Zamora P. A polymorphism in FASL is associated with rituximab response in follicular lymphoma patients. Am J Hematol. 2016 Jun;91(6):E305-7. doi: 10.1002/ajh.24354. Epub 2016 Apr 24. PMID: 26950187.

García-Solano J, García-Solano ME, Torres-Moreno D, Carbonell P, Trujillo-Santos J, Pérez-Guillermo M, Conesa-Zamora P. Biomarkers for the identification of precursor polyps of colorectal serrated adenocarcinomas. Cell Oncol (Dordr). 2016 Jun;39(3):243-52. doi: 10.1007/s13402-016-0269-5. Epub 2016 Feb 1. PMID: 26832730.

Muñoz-Ballester J, Chen-Liang TH, Hurtado AM, Heras I, de Arriba F, García-Malo MD, Iniesta P, Lozano ML, Nieto JB, Ortuño FJ, Osma Mdel M, Padilla J, Teruel-Montoya R, Vicente V, Castilla-Llorente C, Jerez A. Persistent cytotoxic T lymphocyte expansions after allogeneic haematopoietic stem cell transplantation: kinetics, clinical impact and absence of STAT3 mutations. Br J Haematol. 2016 Mar;172(6):937-46. doi: 10.1111/bjh.13917. Epub 2016 Jan 5. PMID: 26728704.

2015

Conesa-Zamora P, García-Solano J, Turpin Mdel C, Sebastián-León P, Torres-Moreno D, Estrada E, Tuomisto A, Wilce J, Mäkinen MJ, Pérez-Guillermo M, Conesa A. Methylome profiling reveals functions and genes which are differentially methylated in serrated compared to conventional colorectal carcinoma. Clin Epigenetics. 2015 Sep 17;7(1):101. doi: 10.1186/s13148-015-0128-7. PMID: 26388956; PMCID: PMC4574063.

Luengo-Gil G, González-Billalabeitia E, Chaves-Benito A, García Martínez E, García Garre E, Vicente V, Ayala de la Peña F. Effects of conventional neoadjuvant chemotherapy for breast cancer on tumor angiogenesis. Breast Cancer Res Treat. 2015 Jun;151(3):577-87. doi: 10.1007/s10549-015-3421-4. Epub 2015 May 13. PMID: 25967462.

Milara J, Outeda-Macias M, Aumente-Rubio MD, Más-Serrano P, Aldaz A, Calvo MV, García-Simón MS, Martin-Barbero M, Padullés-Zamora N, Schoenenberger JA, Saavedra-Aldrich M, Tévar-Alfonso E, Saval A, Pastor-Clerigues A, García M, Margusino-Framiñan L, Montero-Alvarez JL, Merino E, Herrero JI, Beunza M, Conesa-Zamora P, Gimenez-Manzorro A, Comas-Sugrañes D, Cano-Marron M, Jiménez-Mutiloa E, Díaz-Ruíz P, Cortijo J. PEG-Interferon-α ribavirin-induced HCV viral clearance: a pharmacogenetic multicenter Spanish study. Farm Hosp. 2015 Jan 1;39(1):29-43. doi: 10.7399/fh.2015.39.1.8547. PMID: 25680433.

2014

García-Martínez E, Luengo-Gil G, Benito AC, González-Billalabeitia E, Conesa MA, García García T, García-Garre E, Vicente V, Ayala de la Peña F. Tumor-infiltrating immune cell profiles and their change after neoadjuvant chemotherapy predict response and prognosis of breast cancer. Breast Cancer Res. 2014 Nov 29;16(6):488. doi: 10.1186/s13058-014-0488-5. PMID: 25432519; PMCID: PMC4303200.

Salloum-Asfar S, Teruel-Montoya R, Arroyo AB, García-Barberá N, Chaudhry A, Schuetz E, Luengo-Gil G, Vicente V, González-Conejero R, Martínez C. Regulation of coagulation factor XI expression by microRNAs in the human liver. PLoS One. 2014 Nov 7;9(11):e111713. doi: 10.1371/journal.pone.0111713. PMID: 25379760; PMCID: PMC4224396.

Mayor-López L, Tristante E, Carballo-Santana M, Carrasco-García E, Grasso S, García-Morales P, Saceda M, Luján J, García-Solano J, Carballo F, de Torre C, Martínez-Lacaci I. Comparative Study of 17-AAG and NVP-AUY922 in Pancreatic and Colorectal Cancer Cells: Are There Common Determinants of Sensitivity? Transl Oncol. 2014 Oct 24;7(5):590-604. doi: 10.1016/j.tranon.2014.08.001. PMID: 25389454; PMCID: PMC4225658.

Dzhugashvili M, Luengo-Gil G, García T, González-Conejero R, Conesa-Zamora P, Escolar PP, Calvo F, Vicente V, Ayala de la Peña F. Role of genetic polymorphisms in NFKB-mediated inflammatory pathways in response to primary chemoradiation therapy for rectal cancer. Int J Radiat Oncol Biol Phys. 2014 Nov 1;90(3):595-602. doi: 10.1016/j.ijrobp.2014.06.060. Epub 2014 Sep 26. PMID: 25304949.

Heredia-Galvez B, Ruiz-Cosano J, Torres-Moreno D, Español I, Morales-Lara MJ, Pérez-Ceballos E, González-Conejero R, Gutiérrez-Cívicos R, Vicente V, Pérez-Guillermo M, Conesa-Zamora P. Association of polymorphisms in TRAIL1 and TRAILR1 genes with susceptibility to lymphomas. Ann Hematol. 2014 Feb;93(2):243-7. doi: 10.1007/s00277-013-1864-4. PMID: 23959437.

2013

Guillén J, Ferrer-Orta C, Buxaderas M, Pérez-Sánchez D, Guerrero-Valero M, Luengo-Gil G, Pous J, Guerra P, Gómez-Fernández JC, Verdaguer N, Corbalán-García S. Structural insights into the Ca2+ and PI(4,5)P2 binding modes of the C2 domains of rabphilin 3A and synaptotagmin 1. Proc Natl Acad Sci U S A. 2013 Dec 17;110(51):20503-8. doi: 10.1073/pnas.1316179110. Epub 2013 Dec 3. PMID: 24302762; PMCID: PMC3870689.

Vilchez JR, Torres-Moreno D, Martínez-Senac MM, Trujillo-Santos J, Conesa-Zamora P. Evaluation of the association of NKG2C copy number variations with susceptibility to human papillomavirus-induced cervical lesions. Hum Immunol. 2013 Oct;74(10):1352-6. doi: 10.1016/j.humimm.2013.07.006. Epub 2013 Jul 31. PMID: 23911737.

Conesa-Zamora P. Immune responses against virus and tumor in cervical carcinogenesis: treatment strategies for avoiding the HPV-induced immune escape. Gynecol Oncol. 2013 Nov;131(2):480-8. doi: 10.1016/j.ygyno.2013.08.025. Epub 2013 Aug 29. PMID: 23994536.

Ferrer-Marín F, Bellosillo B, Martínez-Avilés L, Soler G, Carbonell P, Luengo-Gil G, Caparrós E, Torregrosa JM, Besses C, Vicente V. Leukemic transformation driven by an ASXL1 mutation after a JAK2V617F-positive primary myelofibrosis: clonal evolution and hierarchy revealed by next-generation sequencing. J Hematol Oncol. 2013 Sep 8;6:68. doi: 10.1186/1756-8722-6-68. PMID: 24011025; PMCID: PMC3847205.

Conesa-Zamora P, Torres-Moreno D, Isaac MA, Pérez-Guillermo M. Gene amplification and immunohistochemical expression of ERBB2 and EGFR in cervical carcinogenesis. Correlation with cell-cycle markers and HPV presence. Exp Mol Pathol. 2013 Oct;95(2):151-5. doi: 10.1016/j.yexmp.2013.06.011. Epub 2013 Jul 1. PMID: 23827764.

Rodríguez-Arcas MJ, García-Jiménez E, Montesinos-Hernández A, Martínez-Martínez F, Conesa-Zamora P. Pharmacotherapeutic Follow-up and Pharmacogenetics of CYP2C9 and CYP3A4 in Antihypertensive Therapy: A Pilot Study in a Community Pharmacy. Ther Innov Regul Sci. 2013 Jul;47(4):489-494. doi: 10.1177/2168479013492736. PMID: 30235515.

Dominguez-Rodriguez A, Avanzas P, Consuegra-Sanchez L, Sanchez-Grande A, Abreu-Gonzalez P, Conesa-Zamora P. Inflammatory markers in blood and thrombus aspirated from patients with acute myocardial infarction with st-segment elevation: ARTERIA trial study design and rationale. Biomarkers. 2013 Jun;18(4):369-72. doi: 10.3109/1354750X.2013.797028. PMID: 23701265.

Conesa-Zamora P, Ruiz-Cosano J, Torres-Moreno D, Español I, Gutiérrez-Meca MD, Trujillo-Santos J, Pérez-Ceballos E, González-Conejero R, Corral J, Vicente V, Pérez-Guillermo M. Polymorphisms in xenobiotic metabolizing genes (EPHX1, NQO1 and PON1) in lymphoma susceptibility: a case control study. BMC Cancer. 2013 May 7;13:228. doi: 10.1186/1471-2407-13-228. PMID: 23651475; PMCID: PMC3649938.

García-Solano J, Conesa-Zamora P, Carbonell P, Trujillo-Santos J, Torres-Moreno D, Rodriguez-Braun E, Vicente-Ortega V, Pérez-Guillermo M. Microsatellite pathologic score does not efficiently identify high microsatellite instability in colorectal serrated adenocarcinoma. Hum Pathol. 2013 May;44(5):759-65. doi: 10.1016/j.humpath.2012.07.020. Epub 2012 Oct 22. PMID: 23089493.

Conesa-Zamora P. Role of cell cycle biomarkers in human papillomavirus related uterine lesions. Curr Pharm Des. 2013;19(8):1412-24. PMID: 23016774.

Cascales A, Pastor-Quirante F, Sánchez-Vega B, Luengo-Gil G, Corral J, Ortuño-Pacheco G, Vicente V, de la Peña FA. Association of anthracycline-related cardiac histological lesions with NADPH oxidase functional polymorphisms. Oncologist. 2013;18(4):446-53. doi: 10.1634/theoncologist.2012-0239. Epub 2013 Apr 10. PMID: 23576480; PMCID: PMC3639532.

Ruiz-Cosano J, Torres-Moreno D, Conesa-Zamora P. Influence of polymorphisms in ERCC5, XPA and MTR DNA repair and synthesis genes in B-cell lymphoma risk. A case-control study in Spanish population. J BUON. 2013 Apr-Jun;18(2):486-90. PMID: 23818366.

Lacruz-Guzmán D, Torres-Moreno D, Pedrero F, Romero-Cara P, García-Tercero I, Trujillo-Santos J, Conesa-Zamora P. Influence of polymorphisms and TNF and IL1β serum concentration on the infliximab response in Crohn’s disease and ulcerative colitis. Eur J Clin Pharmacol. 2013 Mar;69(3):431-8. doi: 10.1007/s00228-012-1389-0. Epub 2012 Sep 8. PMID: 22960943.

Conesa-Zamora P, García-Solano J, García-García F, Turpin Mdel C, Trujillo-Santos J, Torres-Moreno D, Oviedo-Ramírez I, Carbonell-Muñoz R, Muñoz-Delgado E, Rodriguez-Braun E, Conesa A, Pérez-Guillermo M. Expression profiling shows differential molecular pathways and provides potential new diagnostic biomarkers for colorectal serrated adenocarcinoma. Int J Cancer. 2013 Jan 15;132(2):297-307. doi: 10.1002/ijc.27674. Epub 2012 Jun 28. PMID: 22696308.